研究领域:
海洋生物技术、农业生物技术
教育经历:
2000 09 – 2004 07,中国科学院遗传与发育生物学研究所,博士研究生。
工作经历:
2005 04 – 2010 12,俄亥俄州立大学植物病理系(美国),博士后/资深研究助理;
2010 09,入选福建省首批“引进高层次创业创新(百人计划)人才”;
2011 01 – 2018 06,福建省农业科学院生物技术研究所,研究员、创新团队首席专家;
2018 07 – 至今,威尼斯87978797地理与海洋学院,“闽都学者”卓越教授、福州海洋研究院海洋生物技术研发中心主任、海洋生物与药物福建省高校工程研究中心主任;
承担课程:
《海洋技术前沿专题》和《遗传学》
科研成果
主持项目:
1. 短链脱氢酶/还原酶OsSDRlml-OsSDR039基因簇介导水稻二萜化合物代谢及抗病性增强的分子机制,2021.01-2024.12,国家自然科学基金面上项目,58.0万元;
2. 调控稻瘟病抗性的水稻类受体蛋白激酶基因的鉴定和功能解析,2021.01-2024.12,国家自然科学基金---促进海峡两岸科技合作联合基金(重点支持项目),45.0万元(子任务负责人);
3. 硅元素增强水稻对稻瘟病菌抗性的分子机制,2020.11-2023.11,福建省自然科学基金面上项目, 10.0万元;
4. 烟草应答镁、锌、硼、硫胁迫的组学分析及生物标志筛选,2019.10-2023.12,福建省烟草专卖局科技项目(横向),85.0万元(外协单位主持人);
5. 米草综合治理创新平台建设与应用示范,2021.08-2022.06,泉州市水利局科技项目(横向),100.0万元;
6. 闽台水稻种质稻瘟病基础抗性基因资源挖掘及抗性机制研究,国家自然科学基金-海峡联合基金重点项目,2015.01-2018.12, 259.0万元;
7. 稻瘟菌效应因子的规模化鉴定和功能分析,国家自然科学基金面上项目, 2012.01-2015.12, 60万元;
8. 抗病基因介导水稻抗稻瘟病分子网络,福建省自然科学基金杰出青年项目,2011-2014, 30.0万元;福建省自然科学基金杰出青年滚动项目,2014-2017, 50.0万元;
9. 水稻抗稻瘟病基因克隆及分子标记体系建立,福建省公益类科研院所专项重点项目,2017-2019,30.0万元;
10. 福建省“引进高层次创业创新人才(百人计划)”,福建省委组织部/省委人才工作小组,2011.01-2015.12,200.0万元。
代表性论文:
1. Qu M, Zhang Z, Liang T, Niu P, Wu M, Chi W, Chen ZQ, Chen ZJ, Zhang S, Chen S#. Overexpression of a methyl-CpG-binding protein gene OsMBD707 leads to larger tiller angles and reduced photoperiod sensitivity in rice. BMC Plant Biol. 2021, 21:100
2. Li Y, Han Y, Qu M, Chen J, Chen X, Geng X, Wang Z, Chen S#. Apoplastic Cell Death-Inducing Proteins of Filamentous Plant Pathogens: Roles in Plant-Pathogen Interactions.Front. Genet. 2020, 11:661
3. Liang T, Chi W, Huang L, Qu M, Zhang S, Chen ZQ, Chen ZJ, Tian D, Gui Y, Chen X, Wang Z, Tang W# andChen S#. Bulked segregant analysis coupled with whole-genome sequencing (BSA-Seq) mapping identifies a novel pi21 haplotype conferring basal resistance to rice blast disease. Int. J. Mol. Sci. 2020, 21: 2162. doi: 10.3390/ijms21062162
4. Wu M, Liu H, Lin Y, Chen J, Fu Y, Luo J, Zhang Z, Liang K#, Chen S# and Wang F#. In-frame and frame-shift editing of the Ehd1 gene to develop Japonica rice with prolonged basic vegetative growth Periods. Front. Plant Sci. 2020, 11: 307. doi: 10.3389/fpls.2020.00307
5. Chen Z, Zheng W, Chen L, Li C, Liang T, Chen Z, Xu H, Han Y, Kong L, Zhao X, Wang F#, Wang Z# and Chen S#. Green fluorescent protein- and Discosoma sp. red fluorescent protein-tagged organelle marker lines for protein subcellular localization in rice. Front. Plant Sci. 2019, 10: 1421. doi: 10.3389/fpls.2019.01421
6. Guo X, Zhong D, Xie W, He Y, Zheng Y, Lin Y, Chen Z, Han Y, Tian D, Liu W, Wang F, Wang Z, Chen S#. Functional identification of novel cell death-inducing effector proteins from Magnaporthe oryzae. Rice, 2019, 12: 59
7. Zhu Y*, Lin Y*, Chen S*, Liu H, Chen Z, Fan M, Hu T, Mei F, Chen J, Chen L, Wang F. CRISPR/Cas9-mediated functional recovery of the recessive rc allele to develop red rice. Plant Biotechnol. J. 2019, doi:10.1111/pbi.13125
8. Tian D, Yang L, Chen Z, Chen Z, Wang F, Zhou Y, Luo Y, Yang L, Chen S#. Proteomic analysis of the defense response to Magnaporthe oryzae in rice harboring the blast resistance gene Piz-t. Rice, 2018, 11: 47
9. Chen Z, Cheng Q, Hu C, Guo X, Chen Z, Lin Y, Hu T, Bellizzi M, Lu G, Wang GL, Wang Z#, Chen S#, Wang F#. A chemical-induced, seed-soaking activation procedure for regulated gene expression in rice.Front. Plant Sci. 2017, 8: 1447
10. Chen Z, Kong L, Zhou Y, Chen Z, Tian D, Lin Y, Wang F, Chen S#. Endosperm-specific OsPYL8 and OsPYL9 act as positive regulators of the ABA signaling pathway in rice seed germination. Funct. Plant Biol. 2017, 44: 635-645
11. Tian D, Chen Z, Chen Z, Zhou Y, Wang Z, Wang F, Chen S#. Allele-specific marker-based assessment revealed that the rice blast resistance gene Pi2 and Pi9 have not been widely deployed in Chinese indica rice cultivars. Rice, 2016, 9: 19
12. He F, Chen S, Ning Y, Wang G-L. Rice (Oryza sativa) protoplast isolation and its application for transient expression analysis. Cur. Protoc. Plant Biol. 2016, 1: 373-383
13. Park CH, Shirsekar G, Bellizzi M, Chen S, Songkumarn P, Xie X, Shi X, Ning Y, Zhou B, Suttiviriya P, Wang M, Umemura K, Wang GL. The E3 lgase APIP10 cnnects the efector AvrPiz-t to the NLR rceptor Piz-t in rce. PLoS Pathog.2016, 12:e1005529
14. Chen S*, Songkumarn P*, Venu RC*, Gowda M, Bellizzi M, Hu J, Liu W, Ebbole D, Meyers B, Mitchell T, Wang GL. Identification and characterization of in planta-expressed secreted effector proteins from Magnaporthe oryzae that induce cell death in rice. Mol. Plant Microbe Interact. 2013, 26: 191-202
15. Park CH*, Chen S*, Shirsekar G*, Zhou B*, Khang CH, Songkumarn P, Afzal AJ, Ning Y, Wang R, Bellizzi M, Valent B, Wang GL. The Magnaporthe oryzae effector AvrPiz-t targets the RING E3 ubiquitin ligase APIP6 to suppress pathogen-associated molecular pattern-triggered immunity in rice. Plant Cell, 2012, 24: 4748-4762
16. La H, Ding B, Mishra GP, Zhou B, Yang H, Bellizzi M, Chen S, Meyers BC, Peng Z, Zhu JK, Wang GL.A 5-methylcytosine DNA glycosylase/lyase demethylates the retrotransposon Tos17 and promotes its transposition in rice.Proc. Natl. Acad. Sci. U S A, 2011, 108:15498-15503
17. Chen S, Songkumarn P, Liu J, and Wang GL. A versatile zero background T-vector system for gene cloning and functional genomics. Plant Physiol. 2009, 150: 1111-1121
18. Vega-Sanchez ME, Zeng L, Chen S, Leung H, Wang GL. 2008. SPIN1, a K homology domain protein negatively regulated and ubiquitinated by the E3 ubiquitin ligase SPL11, is involved in flowering time control in rice. Plant Cell, 2008,20:1456-1469
19. Gowda M,
20. Chen S, Tao L, Zeng L, Vega-Sanchez ME, Umemura K, and Wang G-L. A highly efficient transient protoplast system for analyzing defence gene expression and protein-protein interactions in rice. Mol. Plant Pathol. 2006, 7: 417-427