陈锦霖

讲师

发布时间:2022-03-11浏览次数:923

研究领域:

    海洋药物


承担课程:

    海洋动植物增养殖学


科研成果


主持项目:

    1. 国家自然科学基金青年科学基金“蛋白质翻译延伸因子42Sp50在罗非鱼卵子发生中的作用和机制研究”,(项目编号:31902352;项目经费:25万;2020.1-2022.12

    2. 药物开发横向课题“条纹斑竹鲨vNAR噬菌体免疫库构建” (项目经费:25万;20219-202212月)

    3. 药物开发横向课题“靶向细胞表面抗原的两种初级抗体库的构建” (项目经费:15万;20222-202212月)


代表性论文:

    1. Chen J, Jiang D, Tan D, Fan Z, Wei Y, Li M. (2017). Heterozygous mutation of eef1a1b resulted in spermatogenesis arrest and infertility in male tilapia. Scientific Reports. (7) 43733.

    2. Tao W, Chen J*, Tan D, Yang J, Wei J, Mathew A, Thomas D, and Wang D. (2018). Transcriptome display during sex determination and differentiation as revealed by RNA-Seq analysis. BMC Genomics. 38(1):11-19.

    3. Chen J, Fan Z, Tan D, Jiang D & Wang D. (2017). A review of genetic advances related to sex control and manipulation in tilapia. Journal of the World Aquaculture Society. (1):11-16.

    4. Jiang D, Chen J*, Zheng F, Tan D, Zhao J Shi H. (2017). Crispr/cas9-induced disruption of wt1a, and wt1b, reveals their different roles in kidney and gonad development in Nile tilapia. Developmental Biology. 428 (1):301-309.

    5.Cheng Y, Chen J,Irum M, Chen J. (2021). Genome-Wide Characterization of the Nuclear Receptor Gene Family in Macrostomum lignano Imply Its Evolutionary Diversification. Frontiers in Marine Science.


专利:

    1. 一种PDL1抗体及其提取方法(ZL 2021 1 0184612.0  陈建明 陈锦霖 赵铁铭)

    2.  降钙素原单域抗体及其应用和试剂盒(ZL 2021 0 524833.6  赵铁铭 陈建明 陈锦霖)

    3. 一种新冠病毒N蛋白鲨鱼单域抗体的制备及其应用(ZL 2021 1 0589206.2 陈锦霖 陈建明 程云英)

    4. 一种条纹斑竹鲨单域抗体的酶标抗体的制备及其应用(ZL2021 1 1132704.0 陈锦霖 姜身飞 陈建明)